At what pressure should CPAP be set for assisting ventilation in severe asthma cases?

In severe asthma cases, the optimal pressure for continuous positive airway pressure (CPAP) is typically set between 5-10 cm H2O. This range is effective in improving ventilation by providing a steady airflow that helps to keep the airways open, reducing the work of breathing and minimizing respiratory distress. By maintaining a positive pressure, CPAP can assist in preventing airway collapse, which is particularly important in the context of asthma exacerbations where airway resistance may be significantly increased.

Setting the pressure too low, below 5 cm H2O, might not provide adequate support for these patients, who are often experiencing significant obstruction. Conversely, setting the pressure above 10 cm H2O can lead to excessive pressure that might cause discomfort or further complications, such as reduced venous return to the heart. Therefore, the selected pressure range of 5-10 cm H2O is designed to balance efficacy and patient tolerance, making it the appropriate choice for assisting ventilation in severe asthma cases.