What is the SBP threshold for TPA eligibility in stroke patients?

The threshold for systolic blood pressure (SBP) in determining tissue plasminogen activator (TPA) eligibility in stroke patients is critically established to ensure patient safety during treatment. Specifically, a systolic blood pressure of less than 185 mmHg is required for TPA administration. This threshold is vital because elevated blood pressure can increase the risk of intracerebral hemorrhage when TPA is given, which could lead to severe complications. Maintaining the SBP below this threshold helps to mitigate risks associated with the thrombolytic therapy.

While other options may suggest varying thresholds, the 185 mmHg mark is aligned with established clinical guidelines, reaffirming that controlling hypertension is paramount upon patient assessment and prior to administering TPA. This careful approach aims to maximize the therapeutic benefits of TPA while minimizing potential adverse effects in acute stroke management.