What is the correct mixing instruction for preparing Ketamine for IV/IO administration?

The correct mixing instruction for preparing Ketamine for IV/IO administration involves mixing a specific amount of Normal Saline with the prescribed dosage of Ketamine to ensure proper dilution and delivery when administering the medication. The chosen answer reflects a common practice within emergency medicine protocols, ensuring that the medication is correctly prepared for safe and effective use in patients.

Mixing 9 ml of Normal Saline with 100 mg of Ketamine strikes a balance between sufficient dilution and concentration, allowing for accurate dosing while minimizing the risk of irritation at the injection site. This preparation method is essential, as it adheres to the guidelines often outlined in emergency protocols, which emphasize the importance of proper medication preparation for intravenous or intraosseous routes.

In contrast, the other options may involve inappropriate ratios or volumes that could lead to either suboptimal dosing or increased risk of adverse effects. Each of those other combinations could result in incorrect concentrations, which is critical in emergency settings where precise dosing is paramount to patient safety and treatment efficacy.