What characterizes severe anaphylactic shock?

Severe anaphylactic shock is characterized by a rapid onset of symptoms resulting from a severe allergic reaction, which can potentially be life-threatening. One of the critical indicators of this condition is the presence of signs and symptoms associated with an allergic reaction, such as hives, difficulty breathing, and gastrointestinal distress. Alongside these symptoms, a significant drop in blood pressure—specifically, a systolic blood pressure (SBP) of less than 100 mmHg—and the absence or weakening of the radial pulse (indicative of shock) highlight the severity of the reaction.

Incorporating changes in circulation, such as hypotension (low blood pressure) and altered pulse, is crucial to identifying the severity of anaphylaxis. This combination of allergic symptoms with cardiovascular instability is what distinguishes it as severe anaphylactic shock that requires immediate medical intervention. It emphasizes the critical need for prompt recognition and treatment to prevent further complications or fatalities from the condition.