How often can adult patients repeat the dose of Zofran for nausea/vomiting?

Adult patients can repeat the dose of Zofran, or ondansetron, for nausea and vomiting every 10 minutes up to a total of 8 mg. This dosing protocol is established to ensure effective management of symptoms while minimizing the risk of adverse effects. By allowing a repeat dose every 10 minutes, clinicians can quickly assess the patient’s response to the medication and provide additional relief if needed, without exceeding the recommended maximum dosage within a short timeframe.

The total limit of 8 mg prevents excessive dosing, which is crucial for maintaining patient safety. Given that Zofran has a relatively long half-life, this repetition aligns well with managing acute episodes of nausea and vomiting while monitoring the patient's condition closely.