What is the caution when administering Calcium Chloride and Sodium Bicarbonate?

The reason for the caution regarding Calcium Chloride and Sodium Bicarbonate is primarily related to their chemical interactions when administered together. When these two substances are mixed in the same IV line without proper flushing, they can react with each other and form a precipitate, which may lead to complications in the patient’s treatment. This can not only result in ineffective therapy but may also present additional risks, such as vessel irritation or blockage.

To safely administer both medications, thorough flushing of the IV line is necessary to clear any residual medication before introducing the second drug. This ensures that the integrity and efficacy of both treatments are maintained, and the patient receives the correct therapeutic benefits without adverse effects. Therefore, care must be taken to prevent their simultaneous administration in the same line without flushing.